Long-Term Suppressive cART Is Not Sufficient to Restore Intestinal Permeability and Gut Microbiota Compositional Changes
February 26, 2021The study explores the long-term effects of cART on markers of gut damage, microbial translocation, and paired gut/blood microbiota composition, with a focus on the role exerted by different drug classes. The results conclude that 24 months of cART only affects the gastrointestinal tract minorly.
Ageism and People With Early-Onset Disability
December 16, 2020This study focuses more generally on those who are aging with a disability and have been living with their disability from a young age. In the study, this classifies those who are born with HIV and the discrimination and long-term problems that they face over time as someone with a disability.
The Current State of HIV and Aging: Findings Presented at the 10th International Workshop on HIV and Aging
December 12, 2020This article summarizes plenary talks from the 10th Annual International Workshop on HIV and Aging, which took place in New York City on October 10 and 11, 2019. Presentation topics included the following: the burdens of HIV-associated comorbidities, aging phenotypes, community engagement, and loneliness; these issues are especially important for older PWH, considering the COVID-19 pandemic.
Evaluation of a combined HIV and geriatrics clinic for older people living with HIV: The Silver Clinic in Brighton, UK
October 19, 2020In an evaluated clinic that worked with aging PLWH, it was found that almost all referrals to the clinic involved comorbidities and suspected geriatric syndrome. Researchers suggested that Geriatricians with specializations in HIV might soon play a key role in the management and care of older people with both HIV and geriatric syndromes.
New York Guidance for Addressing the Needs of Older Patients in HIV Care
July 15, 2020New York Department of Health AIDS Institute: Guidance for Addressing the Needs of Older Patients in HIV Care. The goals include: Raising clinicians’ awareness of the needs and concerns of patients with HIV who are 50 or older; Inform clinicians about an aging-related approach to older patients with HIV; Offering recommendations to help clinicians provide optimal care for this population; Provide resources about aging with HIV for healthcare providers and their patients; Suggest steps to guide medical settings in implementing geriatric care into HIV clinical practice.
Research priorities for rehabilitation and aging with HIV: a framework from the Canada-International HIV and Rehabilitation Research Collaborative (CIHRRC)
May 19, 2020People with HIV are living longer and can experience physical, mental, and social health challenges associated with aging and multimorbidity. Rehabilitation is well-positioned to address disability and maximize healthy aging. In this article, findings from CIHRRC’s aim to identify emerging research priorities in HIV, aging, and rehabilitation from the perspectives of people living with HIV, clinicians, researchers, representatives from community organizations, and policy stakeholders are reported.
Geriatric syndromes in people living with HIV associated with aging and increasing comorbidities: implications for neurocognitive complications of HIV infection
January 7, 2020Many aging people with HIV experience health effects similar to people who are 5-10 years older than them. This includes cognitive decline, something that is highly prevalent in older generations. Researchers look at the relationship between living with HIV and cognitive impairment. This article also addresses body composition changes in people with HIV and the clinical complications.
HIV and Aging in Mainland China: Implications for Control and Prevention
November 26, 2019The last 15 years have witnessed a dramatic change in HIV-related epidemiology amidst improvements in treatment and care in China. With proper treatment, HIV is now considered a chronic disease. As a consequence, many people living with HIV (PLWH) now present age-related comorbidities. Thirteen topical issues were reviewed concerning the epidemiology of aging with HIV in mainland China.
Systemic inflammation and the increased risk of inflamm-aging and age-associated diseases in people living with HIV on long-term suppressive antiretroviral therapy
August 27, 2019This study evaluates the levels of systemic inflammation to better understand the risk of age-associated diseases in PLHIV on long-term suppressive ART using a large number of biomarkers of inflammation and immune activation. This study found that there is still a large amount of inflammation in those who are on ART as in those who were untreated.
Oral Microbiome in HIV-Infected Women: Shifts in the Abundance of Pathogenic and Beneficial Bacteria Are Associated with Aging, HIV Load, CD4 Count, and Antiretroviral Therapy
March 12, 2019The study looked at 16S rDNA-based pyrosequencing to compare the salivary microbiome in three groups: (1) Chronically HIV-infected women >50 years of age (aging); (2) HIV-infected women <35 years of age (young adult); and (3) HIV-uninfected age-matched women.
Geriatric-HIV medicine: the geriatrician’s role
December 10, 2018With the ever-growing population of aging people, the importance of geriatricians with HIV experience is growing. Comprehensive Geriatric Assessment is an important tool that could be used for this specific population, but it is noted that the current model would need to be adjusted to work better with aging PLWH.
Patient and provider perceptions of a comprehensive care program for HIV-positive adults over 50 years of age: The formation of the Golden Compass HIV and aging care program in San Francisco
December 5, 2018People living with HIV (PLWH) are living longer, developing comorbidities and aging-related syndromes. New care models are needed to address the combined burden and complexity of HIV and its comorbidities in this group. The goal of this study is to describe qualitative data from patients and providers that informed the development of a comprehensive care model for older PLWH.
