Systemic inflammation and the increased risk of inflamm-aging and age-associated diseases in people living with HIV on long-term suppressive antiretroviral therapy

Babu, Ambikan, A. T., Gabriel, E. E., Akusjärvi, S. S., Palaniappan, A. N., Sundaraj, V., Mupanni, N. R., Sperk, M., Cheedarla, N., Sridhar, R., Tripathy, S. P., Nowak, P., Hanna, L. E., & Neogi, U. (2019). Systemic inflammation and the increased risk of inflamm-aging and age-associated diseases in people living with HIV on long-term suppressive antiretroviral therapy. Frontiers in Immunology, 10, 1965–1965.

https://healthhiv.org/wp-content/uploads/2022/09/Babu.pdf

  • This study evaluates the levels of systemic inflammation to better understand the risk of age-associated diseases in PLHIV on long-term suppressive ART using a large number of biomarkers of inflammation and immune activation. This study found that there is still a large amount of inflammation in those who are on ART as in those who were untreated.