Aging with HIV in the ART Era
This article from Seminars in Diagnostic Pathology examines the various comorbidities, such as chronic inflammation, associated with aging with HIV.
Current Challenges and Solutions in Research and Clinical Care of Older Persons Living with HIV
This conference summary from AIDS Research and Human Retroviruses looks at the current state of research around inflamm-aging and other age-related comorbidities in PWH.
HIV in the United States by Age
While HIV affects all people in the United States and dependent areas, some age groups are especially affected. Get the latest data on HIV by age from the CDC.
HIV complex care and care coordination: the nurse’s role
Articles suggest that nurses specializing in HIV care are an effective approach to a new era of life-long HIV care. Community nurses whose role is to create and conduct CCPs in a small clinic would enable nurses to work directly with patients to increase the effectiveness of the CCP. Something that would likely not be possible in a large commercial clinical setting.
Senotherapeutics for HIV and aging
Senescence is a hallmark of aging-related diseases that is characterized by stable cell cycle arrest and chronic inflammation. Chronic HIV-1 infection predisposes patients to aging-related illnesses and is similarly marked by a senescence-like phenotype. A better understanding of the role of HIV-1 in aging will inform the development of therapeutics aimed at eliminating senescent cells that drive accelerated physiologic aging.
Long-Term Suppressive cART Is Not Sufficient to Restore Intestinal Permeability and Gut Microbiota Compositional Changes
The study explores the long-term effects of cART on markers of gut damage, microbial translocation, and paired gut/blood microbiota composition, with a focus on the role exerted by different drug classes.
Altered gut microbiota correlates with different immune responses to HAART in HIV-infected individuals
Gut microbiota and immune activation were studied in 36 non-HIV-infected subjects and 58 HIV-infected individuals, including 28 immunological responders and 30 immunological non-responders without comorbidities.
The Current State of HIV and Aging: Findings Presented at the 10th International Workshop on HIV and Aging
This article summarizes plenary talks from the 10th Annual International Workshop on HIV and Aging, which took place in New York City on October 10 and 11, 2019. Presentation topics included the following: the burdens of HIV-associated comorbidities, aging phenotypes, community engagement, and loneliness; these issues are especially important for older PWH, considering the COVID-19 pandemic.
Primary Care Guidance for Persons With Human Immunodeficiency Virus: 2020 Update by the HIV Medicine Association of the Infectious Diseases Society of America
To optimize care engagement, medication adherence, and viral suppression, all people with HIV should be provided timely access to care, and HIV care sites should make the effort to provide care in a way that is linguistically and culturally appropriate. HIV care sites should implement programs that incorporate evidence-based programs to improve HIV care engagement and viral suppression.
Echocardiographic Findings Among Virally Suppressed HIV-Infected Aging Asians Compared with HIV-Negative Individuals
The study looked into the prevalence and risk factors associated with echocardiogram abnormalities among those who are older and living with HIV.