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Pozitively Aging

National HIV Curriculum: HIV in Older Adults

February 5, 2024

The shift of the HIV epidemic to increasingly involve older persons highlights several health care needs: (1) medical care systems with the capacity to provide clinical services for a large cohort of older persons with HIV, (2) active screening programs to detect HIV in older persons, and (3) implementation of strategies to prevent forward transmission of HIV from older persons.

HIV and Aging: Double Stigma

Older people living with HIV may experience intersectional stigma resulting from HIV and ageism. The current review summarizes the scientific literature and focuses on social isolation and lack of social support as key factors in experiencing HIV-related and aging-related stigma.

The Science of Aging: Lessons for HIV at the Interface of Commonality and Heterogeneity

CROI Presentation: “20 years Difference between HIV + vs HIV- in this chart’ – “These things are Happening A lot Earlier for PWH than they should be, by 20 years. I would expect 80 year olds to have this level of syndromes, but these PWH are still 60 yrs old or younger.”

HIV Clinical, Comorbid, and Social Determinants of Health are Linked with Brain Aging

Findings indicate that comorbid and social determinants of health are associated with brain aging in people with HIV, alongside traditional HIV metrics such as viral load and CD4 cell count, suggesting the need for a broadened clinical perspective on healthy aging with HIV, with additional focus on comorbidities, lifestyle changes, and social factors.

Integrating Frailty and Functional Outcomes into Clinical Trials

Considerations of frailty and functional outcomes for better integration and representation of aging patients in clinical trials.

Inflamm-aging: Effects of Chronic Inflammation with HIV

Advances in Antiretroviral therapy (ART) allow people with HIV to live longer with fewer medications. Join us as Dr. Peter Hunt details the connection between chronic inflammation and HIV infection and discusses care considerations and emerging research.

HIV: A personal story

April 8, 2023

University of Oxford’s Nuffield Department of Medicine spoke to one of Associate Professor Lucy Dorrell’s patients about her experiences discovering that she was HIV+.

National HIV/AIDS Aging Awareness Day 2022 Twitter Chat

October 21, 2022

Read the transcript of our Twitter Chat on Aging with HIV at the hashtag #NHAADchat.

Infection with HIV can accelerate aging within the first two to three years of infection, study says

July 18, 2022

Researchers with University of California, Los Angeles (UCLA) looked at blood samples from more than 200 men to compare those infected with HIV to a control group who did not have HIV, and scored them on five different measures of aging.

Fatigue is associated with worse cognitive and everyday functioning in older persons with HIV

May 1, 2022

This study goes into detail about framing the relationship between fatigue, cognition, and everyday functioning in PLWH.

Monocytes in HIV and SIV Infection and Aging: Implications for Inflamm-Aging and Accelerated Aging

February 17, 2022

With ART and the extended lifespan of PLWH, HIV comorbidities also include aging—most likely due to accelerated aging—as well as cardiovascular, neurocognitive disorders, lung and kidney disease, and malignancies. The broad evidence suggests that HIV with ART is associated with accentuated aging and that the age-related comorbidities occur earlier, due in part to chronic immune activation, co-infections, and possibly the effects of ART alone.

HIV and Aging in the Era of ART and COVID-19

February 1, 2022

Our understanding of HIV/AIDS has been reframed in the recent past because the use of novel antiretroviral therapy has enabled clinicians and patients to control the progression of the disease.

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