Unique Gut Microbiome in HIV Patients on Antiretroviral Therapy (ART) Suggests Association with Chronic Inflammation
The article investigated compositional changes in the gut microbiome and its role in chronic inflammation in patients infected with HIV.
Positive Psychological Factors are Linked to Successful Cognitive Aging Among Older Persons Living with HIV/AIDS
This paper examines relationships between psychological factors and successful cognitive aging in PWH.
Forging New Frontiers in HIV and Aging
This editorial looks at the current state of ART, aging with HIV, and factors related to positive aging.
Aging with HIV in the ART Era
This article from Seminars in Diagnostic Pathology examines the various comorbidities, such as chronic inflammation, associated with aging with HIV.
Current Challenges and Solutions in Research and Clinical Care of Older Persons Living with HIV
This conference summary from AIDS Research and Human Retroviruses looks at the current state of research around inflamm-aging and other age-related comorbidities in PWH.
HIV in the United States by Age
While HIV affects all people in the United States and dependent areas, some age groups are especially affected. Get the latest data on HIV by age from the CDC.
HIV complex care and care coordination: the nurse’s role
Articles suggest that nurses specializing in HIV care are an effective approach to a new era of life-long HIV care. Community nurses whose role is to create and conduct CCPs in a small clinic would enable nurses to work directly with patients to increase the effectiveness of the CCP. Something that would likely not be possible in a large commercial clinical setting.
Senotherapeutics for HIV and aging
Senescence is a hallmark of aging-related diseases that is characterized by stable cell cycle arrest and chronic inflammation. Chronic HIV-1 infection predisposes patients to aging-related illnesses and is similarly marked by a senescence-like phenotype. A better understanding of the role of HIV-1 in aging will inform the development of therapeutics aimed at eliminating senescent cells that drive accelerated physiologic aging.
Long-Term Suppressive cART Is Not Sufficient to Restore Intestinal Permeability and Gut Microbiota Compositional Changes
The study explores the long-term effects of cART on markers of gut damage, microbial translocation, and paired gut/blood microbiota composition, with a focus on the role exerted by different drug classes.
Altered gut microbiota correlates with different immune responses to HAART in HIV-infected individuals
Gut microbiota and immune activation were studied in 36 non-HIV-infected subjects and 58 HIV-infected individuals, including 28 immunological responders and 30 immunological non-responders without comorbidities.