HIV: A personal story

University of Oxford’s Nuffield Department of Medicine spoke to one of Associate Professor Lucy Dorrell’s patients about her experiences discovering that she was HIV+.

Fatigue is associated with worse cognitive and everyday functioning in older persons with HIV

Fatigue is prevalent in people living with HIV and in older adults. Research has been associated with a wide range of psychosocial factors, including depression, anxiety, and poor quality of sleep, leading to overall poorer quality of life. Fatigue is also associated with comorbidities such as hypothyroidism, Hepatitis C, disease severity, and treatment status among PLWH. This study goes into detail about framing the relationship between fatigue, cognition, and everyday functioning in PLWH.

Monocytes in HIV and SIV Infection and Aging: Implications for Inflamm-Aging and Accelerated Aging

With ART and the extended lifespan of PLWH, HIV comorbidities also include aging—most likely due to accelerated aging—as well as cardiovascular, neurocognitive disorders, lung and kidney disease, and malignancies. The broad evidence suggests that HIV with ART is associated with accentuated aging and that the age-related comorbidities occur earlier, due in part to chronic immune activation, co-infections, and possibly the effects of ART alone.