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Subject: Chronic Illness

Clusterization of co-morbidities and multi-morbidities among persons living with HIV: a cross-sectional study

Co-morbidities and multi-morbidities are extremely prevalent in people living with HIV. More than 50% of PLHW were multi-morbid and about 30% had three or more comorbidities. Those living with HIV are much more at risk of dying or living with more than one disease.

Oral Microbiome in HIV-Infected Women: Shifts in the Abundance of Pathogenic and Beneficial Bacteria Are Associated with Aging, HIV Load, CD4 Count, and Antiretroviral Therapy

The study looked at 16S rDNA-based pyrosequencing to compare the salivary microbiome in three groups: (1) Chronically HIV-infected women >50 years of age (aging); (2) HIV-infected women <35 years of age (young adult); and (3) HIV-uninfected age-matched women.

Reconciling the evaluation of co-morbidities among HIV care patients in two large data systems: the Medical Monitoring Project and CFAR Network of Integrated Clinical Systems

Data on persons with HIV and their burden of disease is poor and varies from one database to another. A study was performed utilizing two large databases, MMP and CNICS. The results displayed that each database can provide reliable data to monitor HIV co-morbidities in the US.

HIV and aging: Role of the microbiome

The researchers in this study observe gut bacteria and the microbiome to see its impact on those aging with HIV.

Long-Term Mortality in HIV-Infected Individuals 50 Years or Older: A Nationwide, Population-Based Cohort Study

Persons with HIV are more likely to have cardiovascular disease because of the residual virally mediated inflammation and side effects of antiretroviral therapy in addition to traditional cardiovascular disease risk factors.

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