Lewy, T., Hong, B. Y., Weiser, B., Burger, H., Tremain, A., Weinstock, G., Anastos, K., & George, M. D. (2019). Oral Microbiome in HIV-Infected Women: Shifts in the Abundance of Pathogenic and Beneficial Bacteria Are Associated with Aging, HIV Load, CD4 Count, and Antiretroviral Therapy. AIDS research and human retroviruses, 35(3), 276–286.
- The study looked at 16S rDNA-based pyrosequencing to compare the salivary microbiome in three groups: (1) Chronically HIV-infected women >50 years of age (aging); (2) HIV-infected women <35 years of age (young adult); and (3) HIV-uninfected age-matched women. The results displayed new evidence that HIV infection is associated with a shift toward an increased pathogenic footprint of the salivary microbiome.